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This allows you to familiarize yourself with game rules and features prior to playing with real money. Legality Pragmatic Play is known for its top-notch games, and for providing a superior user experience. Its software can be used on mobile devices as well as in various languages. It has been recognized as one of the top casino gaming platforms despite its relatively young age. Its latest releases include Wolves which is a five-reel video slot that has a healthy RTP and impressive graphics. Other notable titles include Wolf Gold and Chilli Heat. Pragmatic trials seek to replicate real-world situations and have the highest external validity. They are usually commissioned by practitioners and policy makers to aid in their decision-making. They can be used to determine the causality of an intervention and its effects. However, they should not be used in lieu for explanatory trials. The concept of pragmatism is controversial and there are doubts about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 made a distinction between explanatory studies, which support the physiological hypothesis or clinical hypothesis, as well as pragmatic trials, that inform policy and practice decision-making. They also proposed the framework for pragmatic trials, dubbed PRECIS.2 This tool attempted to define the features of a pragmatic study, including recruitment, design and delivery of the intervention, and monitoring. The number of pragmatic trials is increasing. A recent Medline search using the terms naturalistic and pragmatic, limited to controlled trials that are randomized (RCTs), yielded 34 articles, as shown in red in Figure 2. This is an indication that the health science community is becoming more sensitive to the issue of pragmatics. It is important to note, however, that the majority were conducted in primary-care settings.